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IgG Subclass 1–4 Immunoassays

The Comprehensive Solution for IgG Determination


Assay characteristics

 N Antiserum IgG/Subclass 1N Antiserum IgG/Subclass 2N Latex IgG3N Latex IgG4
Assay principleLatex-enhanced immunonephelometry
Sample
types
Human serum, EDTA plasma, heparinized plasma
Reference ranges*4.05 – 10.111.69 – 7.860.11 – 0.850.03 – 2.01
Initial measuring range0.85 - 270.35 - 110.033 - 2.10.052 - 3.3
Measuring time6122+6
incl. pre-reaction
2+6
incl. pre-reaction
Once-opened reagent staibilty2 weeks on BN ProSpec® System, 3 days (6 days with evaporation stoppers) on BN™ II System2 weeks on BN ProSpec® System, 3 days (6 days with evaporation stoppers) on BN™ II System2 weeks on BN ProSpec® System, 5 days (10 days with evaporation stoppers) on BN™ II System2 weeks on BN ProSpec® System, 5 days (10 days with evaporation stoppers) on BN™ II System
Calibration frequency4 weeks4 weeks4 weeks4 weeks
Precision
(total CV)
≤ 3% @ 3.6 g/L< 3.0% @ 1.8 g/L≤ 6% @ 0.84 g/L< 3% @ 0.507 g/L

 

*The above reference ranges (2.5th to 97.5th percentile in g/L) were established by testing samples from 279 apparently healthy adults from Central Europe (data on file). Please refer to the download section for pediatric reference ranges.

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